PTPRD Antibody | 6875

PTPRD Antibody | 6875 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Mouse: (100%)

Immunogen: PTPRD antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PTPRD.
The immunogen is located within the first 50 amino acids of PTPRD.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB

Application: PTPRD antibody can be used for detection of PTPRD by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: PTPRD antibody is human specific. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. PTPRD cleavage products are often observed in vivo

Positive Control 1: Cat. No. 1201 - HeLa Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 165, 210 kDa (130 kDa for cleavage product)
Observed: 130 kDa

Validation: N/A

Isoform: N/A

Purification: PTPRD Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PTPRD Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: PTPRD antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: PTPRD Antibody: HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA, Receptor-type tyrosine-protein phosphatase delta, Protein-tyrosine phosphatase delta

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: PTPRD Antibody: PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1, 3) . PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.