PTPRE (PTP epsilon) monoclonal Antibody | MB64720

PTPRE (PTP epsilon) monoclonal Antibody | MB64720 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported,one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region,and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: protein tyrosine phosphatase receptor type E

Molecular Weight: 80.6 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HPTPE; PTPE; R-PTP-EPSILON

Immunogen: Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A