PTPRN Polyclonal Antibody | E-AB-52202

PTPRN Polyclonal Antibody | E-AB-52202 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CA 512, FLJ16131, IA 2, IA 2/PTP, IA2, IA2/PTP, ICA 3, ICA 512, ICA3, ICA512, Islet cell antigen 2, Islet cell antigen 512, Islet cell autoantigen 3, Protein tyrosine phosphatase like N, Protein tyrosine phosphatase like N precursor, Protein tyrosine phosphatase receptor type N, PTP IA 2, PTP IA-2, PTP IA2, PTPIA 2, PTPN, Ptprn, PTPRN protein, PTPRN, R PTP N, R-PTP-N, Receptor type tyrosine protein phosphatase like N, Receptor-type tyrosine-protein phosphatase-like N, RPTPN

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Neuroscience, Signal Transduction

Background: IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family, which contains a transmembrane region, an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.

Concentration: 0.96 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human PTPRN

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A