PUF60 Antibody | 22-425

PUF60 Antibody | 22-425 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 243-542 of human PUF60 (NP_055096.2) .

Research Area: Apoptosis, Cell Cycle, Transcription

Tested Application: WB, IHC, IF, IP

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:100
IP: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: THP-1

Positive Control 2: A-549

Positive Control 3: Mouse brain

Positive Control 4: Mouse thymus

Positive Control 5: Mouse spleen

Positive Control 6: Rat lung

Molecular Weight: Observed: 65kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PUF60, FIR, FLJ31379, RoBPI, SIAHBP1, VRJS

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.