Purified Anti-Human CD11a Monoclonal Antibody | DL22232F

Purified Anti-Human CD11a Monoclonal Antibody | DL22232F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Integrin alpha-L, LFA-1A, CD11A, ITGAL

Reactivity: Human

Application: FCM, WB, IHC

Background: CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: R7-1

Isotype: Mouse IgG1, κ