Purified Anti-Human CD123 Monoclonal Antibody | DL21440F

Purified Anti-Human CD123 Monoclonal Antibody | DL21440F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: IL-3Rα, IL-3 Receptor alpha

Reactivity: Human

Application: FCM, WB, IHC, IP

Background: CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: 6H6

Isotype: Mouse IgG1, κ