Purified Anti-Human CD14 Monoclonal Antibody | DL21461F

Purified Anti-Human CD14 Monoclonal Antibody | DL21461F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Monocyte differentiation antigen CD14, CD14, Myeloid cell-specific leucine-rich glycoprotein

Reactivity: Human

Application: FCM, WB, IHC, IP

Background: CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI) -linked membrane glycoprotein that is also known as the LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: MEM-18

Isotype: Mouse IgG1, κ