Purified Anti-Human CD32 Antibody[IV-3] | E-AB-F1075A

Purified Anti-Human CD32 Antibody[IV-3] | E-AB-F1075A | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Low affinity immunoglobulin gamma Fc region receptor II-b,FCGR2B,IgG Fc receptor II-b,CDw32,Fc-gamma RII-b,Fc-gamma-RIIb,FcRII-b,CD32,FCG2, IGFR2

Swissprot Code: P31994

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgM, κ

Research Areas: Cancer, Immunology, Stem cells

Backgroun: CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300

Purification Method: N/A

Dilution: N/A

Clone: IV-3

Conjugation: Unconjugated

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A