Purified Anti-Human CD35 Monoclonal Antibody | DL20796F

Purified Anti-Human CD35 Monoclonal Antibody | DL20796F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Complement receptor type 1, CR1, C3b/C4b receptor, CD35, CR1, C3BR

Reactivity: Human

Application: FCM, IHC, IP

Background: CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: E11

Isotype: Mouse IgG1, κ