Purified Anti-Human CD7 Monoclonal Antibody | DL20848F

Purified Anti-Human CD7 Monoclonal Antibody | DL20848F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: T-cell antigen CD7, CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, TP41

Reactivity: Human

Application: FCM

Background: CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly) . CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: 124-1D1

Isotype: Mouse IgG1, κ