Purified Anti-Human CD81 Monoclonal Antibody | DL20870F

Purified Anti-Human CD81 Monoclonal Antibody | DL20870F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: CD81 antigen, CD81, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1.Tetraspanin-28, Tspan-28, APA1, TSPAN28

Reactivity: Human

Application: FCM, WB, IHC, IF

Background: CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody) . CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: 1.3.3.22

Isotype: Mouse IgG1, κ