Purified Anti-Human CD86 Antibody[BU63] | E-AB-F1012A

Purified Anti-Human CD86 Antibody[BU63] | E-AB-F1012A | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: T-lymphocyte activation antigen CD86,Cd86,Activation B7-2 antigen,Early T-cell costimulatory molecule 1,ETC-1

Swissprot Code: P42081

Application: FCM,WB,Block,IP

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2b, κ

Research Areas: Cancer, Immunology, Microbiology, Stem cells

Backgroun: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300

Purification Method: N/A

Dilution: N/A

Clone: BU63

Conjugation: Unconjugated

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A