PYCR2 Antibody (Center) [AMR09667G]

PYCR2 Antibody (Center) [AMR09667G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PYCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human PYCR2.

Cellular Localisation: Cytoplasm. Mitochondrion

Molecular Weight: 33637

Clone: Polyclonal

Gene Name: PYCR2

Gene ID: 29920

Function: Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP (+) . Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (PubMed:2722838, PubMed:6894153) . Involved in cellular response to oxidative stress (PubMed:25865492) .

Summary: Tissue Location: Detected in erythrocytes (at protein level) (PubMed:2722838, PubMed:6894153) . Expressed in fetal brain (PubMed:25865492) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2, PYCR2