Q-VD-OPh | 1170

A synthetic peptide that is potent, cell permeable, nontoxic and irreversibly inhibits caspase activity to blocks apoptosis. The new generation of caspase inhibitor is more stable in aqueous environment and exhibits several folds higher activity than the corresponding FMK caspase inhibitors. Q-VD-OPH is the inhibitor of choice for both in vitro and in vivo studies.

Q-VD-Oph is a potent, cell-permeable, non-toxic, next generation pan-caspase inhibitor useful for in vivo studies.

1170 | Q-VD-OPh DataSheet

Alternate Name/Synonyms: Q-Val-Asp-Oph, Q-VD-Oph

Appearance: Lyophilized solid

Formulation: N/A

CAS Number: 1135695-98-5

Structure Available?: Yes

Peptide sequence: Quinolyl-Val-Asp-OPh

Salt Form: No

Molecular Formula: C₂₆H₂₅F₂N₃O₆

Molecular Weight: 513.49

Cell-Permeable?: Yes

Purity: >95% by HPLC

Solubilities: DMSO

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A pan-caspase inhibitor

MDL Number: MFCD20527311

PubChem CID: 11237609

SMILES: CC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2

InChi: InChI=1S/C26H25F2N3O6/c1-14(2)23(31-25(35)19-11-10-15-6-3-4-9-18(15)29-19)26(36)30-20(12-22(33)34)21(32)13-37-24-16(27)7-5-8-17(24)28/h3-11,14,20,23H,12-13H2,1-2H3,(H,30,36)(H,31,35)(H,33,34)

InChi Key: OOBJCYKITXPCNS-UHFFFAOYSA-N