Quinol 1h | 2436

A potent and selective antitumor agent that displays potent activity against renal, colon, and breast cancer cell lines in the NCI 60-cell panel. Exhibits a mean GI₅₀ of 16 nM and a mean LC₅₀ value of 2.24 µM in NCI60-cell-line screen, with LC₅₀ activity in the HCT 116 human colon cancer cell line below 10 nM.

Quinol 1 h is a potent and selective antitumor agent that displays potent activity against renal, colon, and breast cancer cell lines in the NCI 60-cell panel.

2436 | Quinol 1h DataSheet

Alternate Name/Synonyms: 4-(1-Benzenesulfonyl-6-fluoro-1H-indol-2-yl)-4-hydroxy-cyclohexa-2,5-dienone

Appearance: Crystalline solid

Formulation: N/A

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₄FNO₄S

Molecular Weight: 383.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent and selective antitumor agent

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(C=C1)C=CC1(O)C2=CC3=C(N2S(=O)(C4=CC=CC=C4)=O)C=CC=C3

InChi: InChI=1S/C20H15NO4S/c22-16-10-12-20(23,13-11-16)19-14-15-6-4-5-9-18(15)21(19)26(24,25)17-7-2-1-3-8-17/h1-14,23H

InChi Key: HWKQYGBAAMKHDY-UHFFFAOYSA-N