RAB4A monoclonal Antibody | MB0161

RAB4A monoclonal Antibody | MB0161 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: H,M,R

Application: WB ICC

Application Range: WB: 1:1000 ICC: 1:100~300

Background: The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies, exhibits 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possiblity that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab family have been identified, each of which is found at a particular stage of a membrane transport pathway.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of RAB4A and does not cross-react with related proteins

Molecular Weight: Predicted band size:24KDa Observed band size:30KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Ras-related protein Rab-4A; RAB4

Immunogen: Recombinant full length Human RAB4A.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: