552
Rabbit Anti-Human Apolipoprotein AII Affinity Pure | ABMC-A06
- SKU:
- 552-A06-GEN
- Availability:
- IN STOCK
Description
Rabbit Anti-Human Apolipoprotein AII Affinity Pure |A06
Host Species: | Rabbit |
Concentration: | 1 mg/ml (OD 1.35 / 280 nm) |
Antigen: | Human Apolipoprotein AII |
Purification: | Affinity purified |
Buffer: | 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02% NaN3, pH 7.2 |
Specificity | Specifically binds to human apo AII. Dilution for immunoblot and ELISA range: 1,000 to 20,000. |
Use: | The antibody can be used for detection of human apo AII in plasma and lipoproteins, immunoassays, immunoblots, enzyme conjugation, or biotinylation. |
Storage: | -20°C for long-term storage, 4°C for short- term storage. Aliquot to avoid repeated freezing and thawing. |
*These products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.
IMPORTANCE
Apo AII comprises 25% of HDL. It exists in human plasma as a dimer of 2 identical chains of 77 amino acid residues, joined by disulfide. The molecular weight is reported to be 8.7 kDa for a single chain (Brewer et al., 1972).
Studies on mouse reported that apoAII may be proatherogenic (Warden et al., 1993); however, case-control study in the large European Prospective Investigation demonstrated that plasma Apo AII concentrations were strongly inversely correlated with CHD events (Birjmohun et al., 2007).