Description
Rabbit Anti-Human TNF-beta Antibody | 102-P88 | Gentaur UK, US & Europe Distribution
Species: Anti-Human
Host / biotech: Rabbit
Comment: N/A
Label: N/A
Clone / Antibody feature: Rabbit IgG
Subcategory: Polyclonal Antibody
Category: Antibody
Synonyms: LTA; LT; TNFB; TNFSF1
Isotype: N/A
Application: ELISA, WB, N
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: recombinant human TNF-beta
Description: TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized from PBS
Storage Handling Stability: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 4049