Immunoglobulin G (IgG) is part of the family of glycoprotein immunoglobulins which stage immune responses against pathogenic organisms. IgG contributes to the immune response by mobilizing innate immune effector cells and inducing and pro-inflammatory responses. Such proinflammatory responses are mediated by Fcg receptors which interact with sialylated Fc fragments on IgG molecules.
Specificity
This antibody reacts with rabbit IgG and rabbit IgG (Fc) as demonstrated by ELISA. Minimal cross-reactivity detected with Human IgG and Rabbit IgM; little to no cross-reactivity detected with Mouse IgG, Rat IgG, Chicken IgY, Guinea Pig IgG, and Hamster IgG.
Immunogen
Rabbit IgG
Application
Research Category Secondary & Control Antibodies
Research Sub Category Isotype Control Antibodies
Sheep-anti-Rabbit IgG secondary antibody detects level of Rabbit IgG secondary & has been published & validated for use in ELISA.