RAC2 Antibody (C-term) [APR33164G]

RAC2 Antibody (C-term) [APR33164G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This RAC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 178-192 amino acids from the C-terminal region of human RAC2.

Cellular Localisation: Cytoplasm. Note=Membrane-associated when activated

Molecular Weight: 21429

Clone: Polyclonal

Gene Name: RAC2

Gene ID: 5880

Function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.

Summary: Tissue Location: Hematopoietic specific.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, IF

Dilution: WB--1:2000

Synonyms: Ras-related C3 botulinum toxin substrate 2, GX, Small G protein, p21-Rac2, RAC2