RAD51C Antibody| F44332-0.08ML/F44332-0.4ML/R31816

RAD51C Antibody| F44332-0.08ML/F44332-0.4ML/R31816 | Gentaur UK, US & Europe Distribution

Background: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the RAD51C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This RAD51C antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 169-198 from the human protein was used as the immunogen for this RAD51C antibody.

Storage: Aliquot the RAD51C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A