RAD54L2 Polyclonal Antibody | E-AB-10576

RAD54L2 Polyclonal Antibody | E-AB-10576 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Androgen receptor interacting protein 4, Androgen receptor-interacting protein 4, Arip4, ARIP4, HCMV interacting protein;, Helicase ARIP4, HSPC325, RAD54 like 2 (S. cerevisiae), RAD54 like protein 2, RAD54-like protein 2, Rad54l2, SRISNF2L, Steroid receptor interacting SNF2 domain protein

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Signal Transduction

Background: Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1, 467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human RAD54L2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A