Rage Antibody| F43706-0.08ML/F43706-0.4ML/R30250

Rage Antibody| F43706-0.08ML/F43706-0.4ML/R30250 | Gentaur UK, US & Europe Distribution

Background: RAGE, the 'receptor for advanced glycation endproducts' is a transmembrane receptor of the immunoglobulin super family. The interaction between RAGE and its ligands, AGE and HMGB1, is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors. [Wiki]

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the Rage antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Rage antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 76-104 from the mouse protein was used as the immunogen for this Rage antibody.

Storage: Aliquot the Rage antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A