RAI3 (L179) polyclonal Antibody | BS3199

RAI3 (L179) polyclonal Antibody | BS3199 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Retinoic acid-induced protein 3 (RAI3) is a transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis,cell growth, differentiation and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer; selective suppression of signals from RAI3 may have a place in breast cancer treatments.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RAI3 (L179) pAb detects endogenous levels of RAI3 protein.

Molecular Weight: ~42 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Retinoic acid-induced gene 1 protein; RAIG-1; Orphan G-protein coupling receptor PEIG-1; GPRC5A; RAI3; RAIG1

Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human RAI3.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A