Raly (R103) polyclonal Antibody | BS9249

Raly (R103) polyclonal Antibody | BS9249 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Raly, also known as hnRNP associated with lethal yellow homolog, autoantigen p542 or heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNPCL2), is a 306 amino acid protein belonging to the RRM HNRPC family. Localized to the nucleus, Raly is thought to be an RNA-binding protein involved in pre-mRNA splicing. Phosphorylated upon DNA damage, Raly has been found to be a subunit of the spliceosome C complex. Raly is also an autoantigen that is crossreactive with an Epstein-Barr virus protein. Raly is expressed at higher levels in pancreas, liver, skeletal muscle, lung, brain, heart and kidney with lower levels found in placenta. Produced by alternative splicing, Raly is expressed as two isoforms.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Raly (R103) polyclonal Antibody detects endogenous levels of Raly protein.

Molecular Weight: ~ 32 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RNA-binding protein Raly; Autoantigen p542; Heterogeneous nuclear ribonucleoprotein C-like 2; hnRNP core protein C-like 2; hnRNP associated with lethal yellow protein homolog; RALY; HNRPCL2; P542

Immunogen: Synthetic peptide, corresponding to amino acids 70-120 of Human Raly.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: