RanBP9 monoclonal Antibody | MB0163

RanBP9 monoclonal Antibody | MB0163 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Application: WB IP ICC

Application Range: WB: 1:1000 ICC: 1:100~300 IP: 1:50~100

Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins

Molecular Weight: Predicted band size:78KDa Observed band size:95KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BPM-L; BPM90; Ran-binding protein M; RanBPM; RanBP7; BPM-L; BPM90; RANBPM; RanBP7

Immunogen: Recombinant full length Human RanBP9.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: