RASA2 Polyclonal Antibody | E-AB-13557

RASA2 Polyclonal Antibody | E-AB-13557 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: GAP1m, GTPase activating protein of RAS, Ras GTPase activating protein 2, Ras GTPase-activating protein 2, RAS p21 protein activator 2, Rasa2, RASA2

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1, 3, 4, 5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human RASA2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A