RASA3 Polyclonal Antibody | BS65934

RASA3 Polyclonal Antibody | BS65934 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: RASA3 is a inhibitory regulator of the Ras-cyclic AMP pathway and is a member of the GAP1 family of GTPase-activating proteins. It stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. RASA3 is an inositol 1,3,4,5-tetrakisphosphate-binding protein (IP4) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RASA3 Polyclonal Antibody detects endogenous levels of RASA3 protein.

Molecular Weight: 91kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GAP III; GAP1 (IP4BP) ; GAP1IP4BP; GAPIII; GTPase activating protein III; Inositol 1 3 4 5 tetrakisphosphate binding protein; Inositol 1345 tetrakisphosphate binding protein; Ins P4 binding protein; Ins (1 3 4 5) P4 binding protein; Ins (1345) P4 binding protein; Ras GTPase activating protein 3; RAS p21 protein activator 3; RASA 3.RASA3_HUMAN

Immunogen: KLH conjugated synthetic peptide derived from human RASA3:501-600/834

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: