RASSF2 Antibody (Center) [ApR04840G]

RASSF2 Antibody (Center) [ApR04840G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This RASSF2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 123-156 amino acids from the Central region of human RASSF2.

Cellular Localisation: Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1

Molecular Weight: 37790

Clone: Polyclonal

Gene Name: RASSF2

Gene ID: 9770

Function: Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.

Summary: Tissue Location: Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Ras association domain-containing protein 2, RASSF2, KIAA0168