RASSF5 Antibody | 22-908

RASSF5 Antibody | 22-908 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human RASSF5 (NP_872606.1) .

Research Area: Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: THP-1

Positive Control 2: A-549

Positive Control 3: 293T

Positive Control 4: Jurkat

Positive Control 5: Mouse brain

Positive Control 6: Mouse liver

Molecular Weight: Observed: 37kDa, 45kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: NORE1, RAPL, Ras association domain-containing protein 5, New ras effector 1, Maxp1, NORE1A, NORE1B, RASSF3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.