Rat Anti-human Semaphorin 3C Antibody | 101-M721

Rat Anti-human Semaphorin 3C Antibody | 101-M721 | Gentaur UK, US & Europe Distribution

Species: Anti-human

Host / biotech: Rat

Comment: N/A

Label: N/A

Clone / Antibody feature: (#29U11)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: Sema3c; SemE; Semae; 1110036B02Rik

Isotype: IgG2

Application: WB, IHC

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: recombinant human Semaphorin 3C

Description: Semaphorins are a large group of structurally related secreted, GPI-anchored and transmembrane cell signaling molecules. There are 8 major classifications (1-7) of Semaphorins characterized by the existence of a conserved 500 amino acid SEMA domain at the amino terminus. Classes 3, 4, 6, and 7 are found in vertebrates only, whilst class 5 is found in both vertebrates and invertebrates. Each class is then divided into additional subgroups based on shared structural characteristics. Semaphorins primarily function as axon growth cone guidance factors during neuronal development. Semaphorin 3A acts as a chemo-repellent to axons, and an inhibitor of the growth of axons by signaling through receptors, Neuropilin-1and Plexin-A. Recombinant human Semaphorin 3A is a 751 amino acid protein containing the SEMA domain, an immunoglobulin c2-like domain and a basic domain (Arg/Lys rich) near the C-terminus.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 10512