Rat Anti-Mouse ADAM-19 Antibody | 103-M302

Rat Anti-Mouse ADAM-19 Antibody | 103-M302 | Gentaur UK, US & Europe Distribution

Species: Anti-Mouse

Host / biotech: Rat

Comment: N/A

Label: N/A

Clone / Antibody feature: (#11J23)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: Adam19; M [b] ; Mltnb; AL024287

Isotype: IgG2

Application: WB

Detection Range: WB: 1:500-1000.

Species Reactivity/Cross reactivity: Mouse

Antigen: recombinant protein of A Disintegrin and Metalloprotease-like Domain 19 ectodomain

Description: ADAM-19 (a disintegrin and metalloprotease 19; also MADDAM and Meltrinβ) is a 95-100 kDa member of the M12B peptidase family of enzymes. It is expressed on multiple cell types including monocytes, fibroblasts, osteoblasts and dendritic cells. After cleavage of a signal sequence and prodomain, the ectodomain circulates in plasma bound to α2 Macroglobulin. ADAM19 cleaves at sequences present in myelin basic protein, insulin β chain, TNFα, TRANCE and SCF. Over amino acids (aa) 205-705, mouse ADAM19 shares 87% aa sequence identity with human ADAM19.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 11492