Description
Rat Anti-Mouse IL-3 receptor beta Antibody | 103-M253 | Gentaur UK, US & Europe Distribution
Species: Anti-Mouse
Host / biotech: Rat
Comment: N/A
Label: N/A
Clone / Antibody feature: (#42A7)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: Csf2rb2; Bil3; Il3r; AIC2A; Il3rb; Il3rb2; BetaIl3; Csfgmrb
Isotype: IgG1
Application: WB
Detection Range: N/A
Species Reactivity/Cross reactivity: Mouse
Antigen: recombinant mouse protein of IL-3R beta extracellular domain
Description: The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 12984