Description
Rat Anti-Mouse Kremen-1 Antibody | 103-M261 | Gentaur UK, US & Europe Distribution
Species: Anti-Mouse
Host / biotech: Rat
Comment: N/A
Label: N/A
Clone / Antibody feature: (#6K45)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: Kremen1; Krm1; Kremen; AV002070
Isotype: IgG2
Application: WB
Detection Range: N/A
Species Reactivity/Cross reactivity: Mouse
Antigen: Mouse recombinant EC domain of Kremen-1
Description: Kremen (Kringle-containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Two related members, Kremen-1 and -2, have been identified. Kremens bind a subset of the secreted Dickkopf (Dkk) proteins with high affinity. The canonical Wnt signaling pathway receptor complex composed of Wnt, the seven-transmembrane domain receptor Frizzled, and the receptor-related protein 5/6 (LRP5/6) coreceptor, is modulated by Kremens and Dkk proteins.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 84035