Rat Anti-Mouse Stem Cell Antigen 1/Sca-1 Antibody | 103-M477

Rat Anti-Mouse Stem Cell Antigen 1/Sca-1 Antibody | 103-M477 | Gentaur UK, US & Europe Distribution

Species: Anti-Mouse

Host / biotech: Rat

Comment: N/A

Label: N/A

Clone / Antibody feature: (#2M39)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: Ly6a; TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1

Isotype: IgG2

Application: IHC (F)

Detection Range: N/A

Species Reactivity/Cross reactivity: Mouse

Antigen: Mouse recombinant protein of Sca-1

Description: Sca-1 is an 18 kDa phosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly-6) family. Sca-1 is encoded by the strain-specific Ly-6 E/A allelic gene. Its expression on multipotent hematopoietic stem cells (HSC) has been used as a marker of HSCs in mice of both Ly-6 haplotypes. Sca-1-positive HSCs can be found in the adult bone marrow, fetal liver, and mobilized peripheral blood and spleen in the adult animal. However, Sca-1 has also been discovered in several non-hematopoietic tissues and can be used to enrich other progenitor cell populations as well. It is suggested that Sca-1 could be involved in regulating both B and T cell activation.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 110454