Rat TNF-α protein | PRP1213

Rat TNF-α protein | PRP1213 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines

Sequence: Amino acid sequence derived from Rat TNFα (P16599) (Leu80-Leu235) was expressed.

Activity: N/A

protein Lenght: The recombinant Rat TNF-α consists of 156 amino acids and has a predicted molecular mass of 17.2 kDa.

Preparation: E. coli

Purity: >98% as determined by SDS-PAGE

Formulation: Lyophilized from sterile 20 mM tris 50 mM NaCl, pH 8.0.

Kit Component: N/A

Features & Benefits : Endotoxin: <0.1 EU per µg of the protein as determined by the LAL method.

Molecular Weight: 17.2 kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Rat TNF-alpha protein using the buffer we provided not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Rat TNF-α proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.107% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: Tumor necrosis factor α (TNF-α), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-α. TNF-α protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1) . TNF-α is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.

Alternative Names: TNF;TNFA;TNFSF2;DIF ;Tumor Necrosis Factor ;Tumor Necrosis Factor Ligand Superfamily Member;Tumor Necrosis Factor (TNF Superfamily, Member 2) ;Tumor Necrosis Factor Ligand 1F ;Tumor Necrosis Factor-Alpha ;TNF Superfamily, Member 2 ;TNLG1F 3;TNF 5

Search Names: TNF;TNFA;TNFSF2;DIF ;Tumor Necrosis Factor ;Tumor Necrosis Factor Ligand Superfamily Member;Tumor Necrosis Factor (TNF Superfamily, Member 2) ;Tumor Necrosis Factor Ligand 1F ;Tumor Necrosis Factor-Alpha ;TNF Superfamily, Member 2 ;TNLG1F 3;TNF 5

Tag: TNF-α