Recombinant ACE2 Antibody, monoclonal | 11-028

Recombinant ACE2 Antibody, monoclonal | 11-028 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: N/A

Homology: N/A

Immunogen: Recombinant Human ACE2 protein

Research Area: Infectious Disease, COVID-19

Tested Application: WB, IHC

Application: WB:1:1000~4000
IHC:IHC:1:50~100

Specificiy: Human

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein G purified from mice ascites

Clonality: Recombinant Monoclonal

Clone: 180-D-2

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.

Concentration: N/A

Storage Condition: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for 1-2 weeks. Store at -20 ˚C for 12 months. Store at -80 ˚C for long term storage.

Alternate Name: Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, ACEH, ACE-related carboxypeptidase, Metalloprotease MPROT15

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis . Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II.