Recombinant Human BCMA Protein (C-His Tag) | PH0097M1

Recombinant Human BCMA Protein (C-His Tag) | PH0097M1 | Gentaur UK, US & Europe Distribution

Short Description: B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF) . The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Product Type: Cytokine

Form: lyophilized

Purity: Greater than 95% by SDS-PAGE

Storage: -70°C

Buffer: 0.2 μm filtered PBS, pH7.4