LBD

Recombinant Human FGL1 Protein | PH0005E1

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LDB-PH0005E1
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NULL283.00 - NULL809.00

Description

Recombinant Human FGL1 Protein | PH0005E1 | Gentaur UK, US & Europe Distribution

Short Description: Fibrinogen-like protein 1 (FGL1), a liver-secreted protein, is a major LAG-3 functional ligand independent from MHC-II. FGL1 inhibits antigen-specific T cell activation, and ablation of FGL1 in mice promotes T cell immunity. Blockade of the FGL1-LAG-3 interaction by monoclonal antibodies stimulates tumor immunity and is therapeutic against established mouse tumors in a receptor-ligand inter-dependent manner.

Product Type: Recombinant Protein

Form: Liquid

Purity: Greater than 95% by SDS-PAGE

Storage: -70ºC

Buffer: 0.2 μm filtered PBS, pH7.4

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