Recombinant Human IFN-lambda2 (IL-28A) Protein [E. coli] | 100-194S/100-194

Recombinant Human IFN-lambda2 (IL-28A) Protein [E. coli] | 100-194S/100-194 | Gentaur UK, US & Europe Distribution

Species: Human

Host / biotech: E. coli

Comment: N/A

Label: N/A

Clone / Antibody feature: N/A

Subcategory: Cytokines & Growth Factors

Category: Recombinant Protein

Synonyms: IL28A; IFNL2; IL-28A;

Isotype: N/A

Application: N/A

Detection Range: Determined by its ability to activate STAT phosphorylation in an ISRE Luciferase Reporter Assay using human colon carcinoma COLO205 cells. The expected ED50 is 0.3-0.5 ng/ml.

Species Reactivity/Cross reactivity: Human

Antigen: N/A

Description: IFN lambda-1, -2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant murine IFN-lambda2 is a 19.8 kDa protein containing 175 amino acid residues.

Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses

Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)

Formulation: lyophilized

Storage Handling Stability: N/A

Reconstituation: N/A

Molecular Weight: 19.6 kDa

Lenght (aa): 174

Protein Sequence: PVARLHGALP DARGCHIAQF KSLSPQELQA FKRA KDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV

NCBI Gene ID: 282616