Recombinant Human MDC (69 aa) Protein [E. coli] | 100-070S/100-070

Recombinant Human MDC (69 aa) Protein [E. coli] | 100-070S/100-070 | Gentaur UK, US & Europe Distribution

Species: Human

Host / biotech: E. coli

Comment: N/A

Label: N/A

Clone / Antibody feature: N/A

Subcategory: Cytokines & Growth Factors

Category: Recombinant Protein

Synonyms: ADAM11; MDC

Isotype: N/A

Application: N/A

Detection Range: Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml.

Species Reactivity/Cross reactivity: Hamsterr, Mouse, Human

Antigen: N/A

Description: MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant human MDC is an 8.1 kDa protein containing 69 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses

Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)

Formulation: lyophilized

Storage Handling Stability: N/A

Reconstituation: N/A

Molecular Weight: 8.1 kDa

Lenght (aa): 69

Protein Sequence: GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLSQ

NCBI Gene ID: 4185