Recombinant Human TNFRSF10B Protein (C-His Tag) | PH0145M1

Recombinant Human TNFRSF10B Protein (C-His Tag) | PH0145M1 | Gentaur UK, US & Europe Distribution

Short Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL . The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.

Product Type: Cytokine

Form: lyophilized

Purity: Greater than 95% by SDS-PAGE

Storage: -70°C

Buffer: 0.2 μm filtered PBS, pH7.4