Recombinant Human TPO Protein [E. coli] | 100-109S/100-109/100-109-SC

Recombinant Human TPO Protein [E. coli] | 100-109S/100-109/100-109-SC | Gentaur UK, US & Europe Distribution

Species: Human

Host / biotech: E. coli

Comment: N/A

Label: N/A

Clone / Antibody feature: N/A

Subcategory: Cytokines & Growth Factors

Category: Recombinant Protein

Synonyms: TNF; DIF; TNFA; TNFSF2; TNF-alpha

Isotype: N/A

Application: N/A

Detection Range: The ED50 as determined by the dose-dependant stimulation of MO7e cells is < 1 ng/ml (1x106 units/mg).

Species Reactivity/Cross reactivity: Human

Antigen: N/A

Description: TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

Purity Confirmation: > 98% by SDS-PAGE

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: N/A

Reconstituation: N/A

Molecular Weight: 18.6 kDa

Lenght (aa): 174

Protein Sequence: SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL

NCBI Gene ID: 7124