Recombinant Mouse IL-15 Protein [E. coli] | M10-022S/M10-022

Recombinant Mouse IL-15 Protein [E. coli] | M10-022S/M10-022 | Gentaur UK, US & Europe Distribution

Species: Mouse

Host / biotech: E. coli

Comment: N/A

Label: N/A

Clone / Antibody feature: N/A

Subcategory: Cytokines & Growth Factors

Category: Recombinant Protein

Synonyms: Il15; IL-15; AI503618

Isotype: N/A

Application: N/A

Detection Range: The ED50 was determined by the stimulation of the proliferation of murine CTLL-2 cells is < 5.0 ng/ml, corresponding to a specific activity of > 2 x 105 units/mg.

Species Reactivity/Cross reactivity: Human, Mouse, Rat

Antigen: N/A

Description: IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant murine IL-15 is a 13.3 kDa protein consisting of 115 amino acid residues.

Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses

Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)

Formulation: lyophilized

Storage Handling Stability: N/A

Reconstituation: N/A

Molecular Weight: 13.3 kDa

Lenght (aa): 115

Protein Sequence: MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS

NCBI Gene ID: 16168