Recombinant Mouse MDC (CCL22) Protein [E. coli] | M10-033S/M10-033

Recombinant Mouse MDC (CCL22) Protein [E. coli] | M10-033S/M10-033 | Gentaur UK, US & Europe Distribution

Species: Mouse

Host / biotech: E. coli

Comment: N/A

Label: N/A

Clone / Antibody feature: N/A

Subcategory: Cytokines & Growth Factors

Category: Recombinant Protein

Synonyms: Ccl22; MDC; DCBCK; ABCD-1; Scya22

Isotype: N/A

Application: N/A

Detection Range: Determined by its ability to chemoattract human activated lymphocytes using a concentration of 10.0-100.0 ng/ml.

Species Reactivity/Cross reactivity: Human, Mouse

Antigen: N/A

Description: MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant murine MDC is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses

Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)

Formulation: lyophilized

Storage Handling Stability: N/A

Reconstituation: N/A

Molecular Weight: 7.8 kDa

Lenght (aa): 68

Protein Sequence: GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS

NCBI Gene ID: 20299