RelB polyclonal Antibody | BS91165

RelB polyclonal Antibody | BS91165 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC/IF IHC IP

Application Range: WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: The NFκB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The DNA binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFκB subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFκB homodimers. However, Rel B/p50 heterodimers, in contrast to NFκB heterodimers, transactivates transcription of promotors containing κB binding sites.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: RelB polyclonal Antibody detects endogenous levels of RelB protein.

Molecular Weight: 62 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RELB, I REL, I-Rel, IREL, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3, relB, RELB, Reticuloendotheliosis viral oncogene homolog B, Transcription factor Rel B, Transcription factor RelB, v rel avian reticuloendotheliosis viral oncogene homolog B, v rel reticuloendotheliosis viral oncogene homolog B,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: