Remdesivir | B2997

Remdesivir is a nucleoside analogue with antiviral activity. It inhibits Middle East respiratory syndrome coronavirus (MERS-CoV)- or severe acute respiratory syndrome coronavirus (SARS-CoV)-infected HAE cultures with EC₅₀ values of 74 nM and 69 nM. It inhibits murine hepatitis virus (MHV) with an EC₅₀ of 30 nM in delayed brain tumor (DBT) cells.

Remdesivir is a nucleoside analogue with antiviral activity. It inhibits Middle East respiratory syndrome coronavirus (MERS-CoV)- or severe acute respiratory syndrome coronavirus (SARS-CoV)-infected HAE cultures with EC₅₀ values of 74 nM and 69 nM. It inhibits murine hepatitis virus (MHV) with an EC₅₀ of 30 nM in delayed brain tumor (DBT) cells.

B2997 | Remdesivir DataSheet

Alternate Name/Synonyms: 2-Ethylbutyl (2S)-2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; 2-ethylbutyl ((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate; GS-5734

Appearance: White to off-White crystalline powder

Formulation:

CAS Number: 1809249-37-3

Structure Available?: True

Peptide sequence:

Salt Form: False

Molecular Formula: C₂₇H₃₅N₆O₈P

Molecular Weight: 602.58

Cell-Permeable?: True

Purity: >99%

Solubilities: ~125 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A nucleoside analogue with antiviral activity

MDL Number: MFCD31657351

PubChem CID: 121304016

SMILES: CCC(CC)COC(=O)C(C)NP(=O)(OCC1C(C(C(O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4

InChi: InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)

InChi Key: RWWYLEGWBNMMLJ-YSOARWBDSA-N