Resistin, rat recombinant | 4561

Resistin is a new member to the family of adipocyte-secreted proteins. The biological functions of Resistin as well as its molecular target are larGely unknown. Whether it promotes or antagonizes insulin action is still unclear. Recombinant rat Resistin is an 11.9 kDa protein consisting of 94 amino acid residues and 16 additional amino acids residues – His Tag.

4561 | Resistin rat recombinant DataSheet

Biomolecule/Target: Resistin

Synonyms: Cysteine-rich secreted protein FIZZ3, Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12--like 2, RSTN, XCP1, RETN1, MGC126603, MGC126609.

Alternates names: Fibroblast Growth Factor-16, FGFG

Taglines: A cysteine-rich protein resulting in high LDL

NCBI Gene ID #: 8823

NCBI Gene Symbol: FGF16

Gene Source: Human

Accession #: O43320

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by the dose dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is 0.5 ng/ml corresponding to a specific activity of 2 x 10^6 units/mg.

Biological activity: Determined by the dose dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is 0.5 ng/ml corresponding to a specific activity of 2 x 10^6 units/mg.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 23.6 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 5 mM Tris, pH 9.0, 0.1 M L-Arginine and 0.4 mM DTT.

Reconstitution Instructions: FGF-16 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant human FGF-16 is a 23.6 kDa protein consisting of 206 amino acid residues.

Amino acid sequence: AEVGGVFASL DWDLHGFSSS LGNVPLADSP GFLNERLGQI EGKLQRGSPT DFAHLKGILR RRQLYCRTGF HLEIFPNGTV HGTRHDHSRF GILEFISLAV GLISIRGVDS GLYLGMNERG ELYGSKKLTR ECVFREQFEE NWYNTYASTL YKHSDSERQY YVALNKDGSP REGYRTKRHQ KFTHFLPRPV DPSKLPSMSR DLFHYR