RFC3 Antibody | XW-7875

RFC3 Antibody | XW-7875 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Rat

Homology: N/A

Immunogen: 1-356

Research Area: Other

Tested Application: E, WB

Application: Activator 1 38 kDa subunit antibody can be used for the detection of Activator 1 38 kDa subunit by ELISA and Western Blot, may also work for ICC and IHC.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 40.6 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: RFC3 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: Replication factor C subunit 3, Activator 1 38 kDa subunit, A1 38 kDa subunit, RFC38, Replication factor C 38 kDa subunit, RF-C 38 kDa subunit, Replication factor C subunit 3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: The elongation of primed DNA templates by DNA polymerase Δ and ε requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.

SUBUNIT: Heterotetramer of subunits of 40, 38, 37, and 36.5 kDa that can form a complex either with a fifth 140/145 kDa unit, or with RAD17. The former interacts with PCNA in the presence of ATP, while the latter has ATPase activity but is not stimulated by PCNA.