RGS17 polyclonal Antibody | BS60229

RGS17 polyclonal Antibody | BS60229 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The regulators of G protein signaling (RGS) proteins inhibit heterotrimeric G protein signaling. RGS proteins work by functioning as GTPase-activating proteins (which increase the GTPase activity of G protein a-subunits) thereby driving G proteins into their inactive GDP-bound form. The human gene that encodes RGS17 (regulator of G protein signaling 17, RGS17) contains 4 exons, spans more than 33 kb and maps to chromosome 6q25.3; the mouse Rgs17 gene maps to chromosome 10 as determined by interspecific backcross mapping. RGS17 is a member of the RZ/A protein family. RZ/A proteins have a simple structure that consists of a conserved amino-terminal cysteine string motif, RGS box and short carboxyl-terminal, which confer GAP activity and the ability to undergo covalent modification and associate with other proteins (at their amino-termini) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RGS17 polyclonal Antibody detects endogenous levels of RGS17 protein.

Molecular Weight: ~ 18 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Regulator of G-protein signaling 17; RGS17

Immunogen: A synthetic peptide corresponding to residues in Human RGS17.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: